Half-life extension and pharmacokinetics (PK) tuning expression vectors. Features pH-dependent FcRn binding enhancements (LA, LS, YTE, QL, YTE+KF, N434A, V308P) engineered to extend in vivo circulating half-life up to 3–4 fold, alongside FcRn-abrogating variants (I253A) for rapid clearance applications and diagnostic imaging.
Showing all 8 results
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Human IgG1 (I253A)
$680.00 -
Human IgG1 (LA: M428L/N434A)
$680.00 -
Human IgG1 (LS: M428L/N434S)
$680.00 -
Human IgG1 (N434A)
$680.00 -
Human IgG1 (T250Q/M428L)
$680.00 -
Human IgG1 (V308P)
$680.00