High-affinity Fc-engineered expression vectors designed to maximize effector function. Incorporates targeted amino acid substitutions (e.g., GASDALIE, ADE, DLE, DE, and G236A) in the CH2 domain to significantly enhance FcγRIIIa binding affinity, driving potent antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP) for oncology and infectious disease applications.
Showing all 5 results
-
Human IgG1 (ADE)
$680.00 -
Human IgG1 (DE)
$680.00 -
Human IgG1 (DLE)
$680.00 -
Human IgG1 (G236A)
$680.00 -
Human IgG1 (GASDALIE)
$680.00