Background
Cetuximab is a recombinant chimeric human/mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and competitively inhibits the binding of EGF. Cetuximab is used to treat colorectal cancer as well as squamous cell carcinoma of the head and neck.
Product Details
| Reactivity | Human |
| Specificity | Detects human EGFR in direct ELISA. This non-therapeutic antibody uses the same variable region sequences (VH, VL) as the therapeutic antibody Cetuximab. This product is for research use only. |
| Source | Recombinant Monoclonal Human IgG1 Clone #FB025 |
| Purification | Protein A/G purified from CHO cell culture supernatant |
| Immunogen | Human EGFR |
| Endotoxin Level | <0.10 EU per 1 µg of the antibody by the LAL method |
| Formulation | 0.2 µm filtered solution in PBS |
| Applications | • Flow Cytometry: 0.25 µg/106 cells |
| Reconstitution | Reconstitute at 0.5 mg/ml in sterile 1xPBS |
| Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at -20 to -70°C |
| Storage Conditions | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. • 12 months from the date of receipt at -20 to -70°C as supplied. • 1 month at 2 to 8°C under sterile conditions |