EAB-057 Datasheet
TNFR2 Recombinant Human Monoclonal Antibody
Recombinant chimeric antibody (clone 5C5), expressed in Chinese Hamster Ovary cells (CHO), is capable of binding to human TNFR2.
Tumor necrosis factor receptor 2 (TNFR2), also known as tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) and CD120b, is one of two membrane receptors that binds tumor necrosis factor-alpha (TNFα). TNFR2 mediates most of the metabolic effects of TNFα. This TNFR2 monoclonal antibody is developed from phage display technologies from rabbit naïve scFv library (SKU: ADL-09). It is a rabbit/human chimeric recombinant monoclonal antibody that binds specifically to human TNFR2, and it can neutralize the bioactivity of human TNFR2.
PROPERTIES
| species reactivity | human |
| recombinant | expressed in Chinese Hamster Ovary cells (CHO) |
| applications | ELISA, WB, IHC, Flow Cyt, neutralization |
| antibody form | affinity purified immunoglobulin |
| clone | 5C5 |
| purity | >95% (SDS-PAGE) |
| form | 0.015 M PBS, 0.05% NaN3, pH7.2 |
| concentration | ~ 1 mg/ml |
| isotype | human IgG1, k |
| Fc engineering | n/a; wild type |
- Store at -20°C. Recombinant monoclonal antibodies are guaranteed stable for 12 months when properly stored.