DNA Aptamer against Platelet Derived Growth Factor BB

DNA Aptamer against Platelet Derived Growth Factor BB

$149.00$298.00

DNA aptamer against platelet derived growth factor BB (PDGF-BB)

SKU: APT-013 Category:

DNA aptamer against Platelet Derived Growth Factor BB (PDGF-BB)

Background

Platelet-derived growth factor BB (PDGF-BB) is a protein that promotes cell growth and tissue repair. It’s produced by platelets, macrophages, mast cells, and hepatocytes. PDGF-BB has many roles, including:

  • Bone formation: PDGF-BB promotes osteoblast development and bone formation. In animal studies, PDGF-BB improved bone density and fracture healing.
  • Wound healing: PDGF-BB promotes the infiltration of neutrophils and macrophages to the site of injury. It also stimulates fibroblasts to secrete new extracellular matrix. PDGF-BB-treated wounds have increased numbers of fibroblasts and granulation tissue.
  • Skin rejuvenation: PDGF-BB can be used in microneedling to improve skin texture and tone.
  • Angiogenesis: PDGF-BB can stimulate angiogenesis in vivo and in tumors.
  • Brain injury: PDGF influences the proliferation of neuroglia in the brain and can help with brain injury.

Product Specification

Aptamer type: DNA aptamer

Aptamer length: 40 bp

Affinity KD: 3.0 nM

Storage: keep at -20°C. DNA aptamers are guaranteed stable for 12 months when properly stored.

Weight 0.5 lbs
Dimensions 1 × 1 × 1 in
Size

10 nmol, 30 nmol

DOCUMENTATION

Data Sheet

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