Human PD-1 Monoclonal Antibody (Research Grade Nivolumab Biosimilar)

Human PD-1 Monoclonal Antibody (Research Grade Nivolumab Biosimilar)

$350.00$2,390.00

Human PD-1 Monoclonal Antibody (Research Grade Pembrolizumab Biosimilar)

Background

Nivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation S228P for additional stability and reduced variability. As a PD-1 blocking antibody, Nivolumab is used to treat melanoma, non small-cell lung cancer, renal cell cancer, head and neck cancer, and Hodgkin lymphoma.

 

Product Details

ReactivityHuman
SpecificityDetects human PD-1 in direct ELISA. This non-therapeutic antibody uses the same variable region sequences (VH, VL) as the therapeutic antibody Nivolumab. This product is for research use only.
SourceRecombinant Monoclonal Human IgG1 Clone #FB008
PurificationProtein A/G purified from CHO cell culture supernatant
ImmunogenHuman PD-1
Endotoxin Level<0.10 EU per 1 µg of the antibody by the LAL method
Formulation0.2 µm filtered solution in PBS
Applications• Flow Cytometry: 0.25 µg/106 cells
ReconstitutionReconstitute at 0.5 mg/ml in sterile 1xPBS
ShippingThe product is shipped with polar packs. Upon receipt, store it immediately at -20 to -70°C
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
• 12 months from the date of receipt at -20 to -70°C as supplied.
• 1 month at 2 to 8°C under sterile conditions
Weight 0.5 lbs
Dimensions 1 × 1 × 1 in

DOCUMENTATION

Datasheet

Services

Recombinant Antibody ProductionHigh Quality Animal-free Antibody Production via Transient Transfection in CHO or HEK293 PlatformsLearn More
Antibody Fragments ProductionHigh Quality scFv, Fab, VHH Design & Production in Mammalian or Bacterial Expression SystemsLearn More
Biosimilar Antibody ProductionHigh Quality Animal-free Biosimilar Antibody Production via Transient Transfection in CHO Cell PlatformLearn More
Bispecific Antibody ProductionHigh Quality Animal-free Bispecific Antibody Production in Mammalian or Bacterial Expression SystemsLearn More
Antibody Isotype SwitchingSwitching Antibody to any Isotype and Any SpeciesLearn More