Human CTLA-4 Monoclonal Antibody (Research Grade Ipilimumab Biosimilar)

Human CTLA-4 Monoclonal Antibody (Research Grade Ipilimumab Biosimilar)

$350.00$2,390.00

Human CTLA-4 Monoclonal Antibody (Research Grade Ipilimumab Biosimilar)

Background

Ipilimumab is a human cytotoxic T-lymphocyte antigen 4 (CTLA-4) blocking antibody used to treat metastatic or unresectable melanoma. Ipilimumab is a fully humanized IgG1 monoclonal antibody that blocks cytotoxic T lymphocyte antigen-4 (CTLA-4). Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes.

 

Product Details

ReactivityHuman
SpecificityDetects human CTLA-4 in direct ELISA. This non-therapeutic antibody uses the same variable region sequences (VH, VL) as the therapeutic antibody Ipilimumab. This product is for research use only.
SourceRecombinant Monoclonal Human IgG1 Clone #FB024
PurificationProtein A/G purified from CHO cell culture supernatant
ImmunogenHuman CTLA-4
Endotoxin Level<0.10 EU per 1 µg of the antibody by the LAL method
Formulation0.2 µm filtered solution in PBS
Applications• Flow Cytometry: 0.25 µg/106 cells
ReconstitutionReconstitute at 0.5 mg/ml in sterile 1xPBS
ShippingThe product is shipped with polar packs. Upon receipt, store it immediately at -20 to -70°C
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
• 12 months from the date of receipt at -20 to -70°C as supplied.
• 1 month at 2 to 8°C under sterile conditions
Weight 0.5 lbs
Dimensions 1 × 1 × 1 in

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Services

Recombinant Antibody ProductionHigh Quality Animal-free Antibody Production via Transient Transfection in CHO or HEK293 PlatformsLearn More
Antibody Fragments ProductionHigh Quality scFv, Fab, VHH Design & Production in Mammalian or Bacterial Expression SystemsLearn More
Biosimilar Antibody ProductionHigh Quality Animal-free Biosimilar Antibody Production via Transient Transfection in CHO Cell PlatformLearn More
Bispecific Antibody ProductionHigh Quality Animal-free Bispecific Antibody Production in Mammalian or Bacterial Expression SystemsLearn More
Antibody Isotype SwitchingSwitching Antibody to any Isotype and Any SpeciesLearn More