CD19/CD3 Bispecific Antibody (Research Grade Blinatumomab)

CD19/CD3 Bispecific Antibody (Research Grade Blinatumomab)

$289.00$889.00

CD19/CD3 Bispecific T cell-engaging (BiTE) Antibody (Research Grade Blinatumomab)

SKU: BSA-001 Category:

Background

Blinatumomab is a bispecific T-cell engager (BiTE). It enables a patient’s T cells to recognize malignant B cells. A molecule of blinatumomab combines two binding sites: a CD3 site for T cells and a CD19 site for the target B cells. CD3 is part of the T cell receptor. Blinatumomab works by linking these two cell types and activating the T cell to exert cytotoxic activity on the target cell. CD3 and CD19 are expressed in both pediatric and adult patients, making blinatumomab a potential therapeutic option for both pediatric and adult populations.

 

Product Details

ReactivityHuman
SpecificityDetects human CD19 and Human CD3ε in direct ELISA. This product is for research use only.
SourceCHO cell transient transfection
SequenceHuman CD19 scFv+Human CD3ε scFv+6xHis tag (N-terminus to C-terminus)
PurificationAffinity purified from CHO cell culture supernatant
Purity>95% measured by SDS-PAGE.
Predicted MW54.1 kDa
ImmunogenHuman CD19 and Human CD3ε
Endotoxin Level<0.10 EU per 1 µg of the antibody by the LAL method
Formulation0.2 µm filtered solution in PBS
ReconstitutionReconstitute at 0.5 mg/ml in sterile 1xPBS
ShippingThe product is shipped with polar packs. Upon receipt, store it immediately at -20 to -70°C
Storage ConditionsUse a manual defrost freezer and avoid repeated freeze-thaw cycles.
• 12 months from the date of receipt at -20 to -70°C as supplied.
• 1 month at 2 to 8°C under sterile conditions
Weight 0.5 lbs
Dimensions 1 × 1 × 1 in
size

50 µg, 200µg

Services

Recombinant Antibody ProductionHigh Quality Animal-free Antibody Production via Transient Transfection in CHO or HEK293 PlatformsLearn More
Antibody Fragments ProductionHigh Quality scFv, Fab, VHH Design & Production in Mammalian or Bacterial Expression SystemsLearn More
Biosimilar Antibody ProductionHigh Quality Animal-free Biosimilar Antibody Production via Transient Transfection in CHO Cell PlatformLearn More
Bispecific Antibody ProductionHigh Quality Animal-free Bispecific Antibody Production in Mammalian or Bacterial Expression SystemsLearn More
Antibody Isotype SwitchingSwitching Antibody to any Isotype and Any SpeciesLearn More